Figure 4

Effects of ERRα knockdown on TGF-β-induced migration and invasion. The migratory and invasive capabilities in Ishikawa and HEC-1A cells treated with TGF-β, after ERRα knockdown, were evaluated using trans-well cell culture and Matrigel invasion chamber systems. Data represent the mean ± standard error of the mean (Ishikawa cells, n = 2; HEC-1A cells, n = 3; A,B). P values are based on one-way ANOVA with post-hoc Tukey’s multiple comparison test. *P < 0.05; **P < 0.01.