Figure 8

Comparison between each crystallographic RGD molecule and the best pose obtained by AutodockVina docking software28 (green) in the binding pocket. (a) α5β1 (PDB ID 3VI4)7. (b) αIIbβ3 (PDB ID 2VDR)20 and (c) αvβ3 (PDB ID 1L5G)2. The amino acids and hydrogen bonds involved mainly in the binding for each crystallographic integrin were highlighted and determined by LIGPLOT + program22.