Table 1 Baseline characteristics.
Variable | N = 85 | Benign | Malignant | p |
|---|---|---|---|---|
Patient | n = 62 | n = 23 | ||
Age (years), mean ± SD | 58.2 ± 13.4 | 57.0 ± 13.7 | 65.4 ± 9.8 | 0.003a |
Sex (%) | ||||
Male | 35 (41.2) | 22 (35.5) | 13 (56.5) | 0.080a |
Female | 50 (58.8) | 40 (64.5) | 10 (43.5) | |
Location of cystic lesion (%) | ||||
Head | 29 (34.1) | 20 (32.3) | 9 (39.1) | 0.031a |
Body | 25 (29.4) | 23 (37.1) | 2 (8.7) | |
Tail | 31 (36.5) | 19 (30.6) | 12 (52.2) | |
Connection of main pancreatic duct and cyst (%) | ||||
Present | 34 (40.0) | 16 (25.8) | 18 (78.3) | <0.001a |
Absent | 51 (60.0) | 46 (74.2) | 5 (21.7) | |
Type of cyst (%) | ||||
Monolocular | 16 (18.8) | 15 (24.2) | 1 (4.3) | 0.058b |
Multilocular | 69 (81.2) | 47 (75.8) | 22 (95.7) | |
CEA (ng/mL), median (IQR) | 243.6 (17.0–8325.3) | 132.3 (4.8–1232.2) | 1407.1 (111.5–30300.0) | 0.002c |
CA19-9 (LU/mL), median (IQR) | 4740.0 (411.6–357855.0) | 3273.0 (305.4–346927.5) | 33180.0 (1018.0–550000.0) | 0.306c |
CA125 (U/mL), median (IQR) | 45.5 (6.5–1300.3) | 52.5 (9.8–1435.8) | 33.0 (4.0–1070.0) | 0.406c |
Amylase (U/L), median (IQR) | 3101.0 (112.0–25917.5) | 2934.0 (116.8–38837.8) | 3430.0 (100.0–11892.0) | 0.318c |
Cyst fluid sampling procedure (%) | ||||
Surgery specimen | 59 (69.4) | 38 (61.3) | 21 (91.3) | 0.008a |
EUS-FNA | 26 (30.6) | 24 (38.7) | 2 (8.7) | |
Malignant predictive value by AI, median (range) | 0.068 (0.00–0.99) | 0.049 (0.00–0.79) | 0.928 (0.05–0.99) | <0.001c |
Malignant predictive value by AI using only CEA, median (range) | 0.101 (0.01–0.97) | 0.072 (0.01–0.80) | 0.902 (0.07–0.97) | <0.001c |