Figure 6
Correlation between impaired contraction of AAA patient SMC and clinical characteristics. (a) Mean contractile response of Control (▲; n = 6), patients who underwent primary aneurysm repair (Primary surgery; n = 17) and patients who underwent secondary surgery for endoleak repair (Endoleak repair; n = 4) derived from multiple experiments. (b) Maximum contractile response of Control (▲; n = 6), patients who underwent primary aneurysm repair (Primary surgery; n = 17) and patients who underwent secondary surgery for endoleak repair (Endoleak repair; n = 4). SMC obtained during endoleak repair exhibit a trend of lower contractility compared to control group (p = 0.050). (c) Mean contractile response of Control (▲; n = 6), Current non-smokers; n = 16 and Current smokers; n = 5 derived from multiple experiments. (d) Maximum contractile response of Control (▲; n = 6), Current non-smokers; n = 16 and Current smokers; n = 5. Patients with normal contraction are marked with ● and patients with low contraction (more than 2 SD bellow the mean of the control group) are marked with ○. SMC of patients who currently smoke exhibit impaired contractility compared to the control group (p = 0.030). Boxplots are shown as median with range and tested with Mann-Whitney U test.
