Figure 2

SHRSP males have larger adipocytes in the PVAT surrounding the third-order mesenteric arteries relative to females. PVAT surrounding the mesenteric artery was weighed (3 vessels/animal) in age matched (16 weeks old) male (n = 10) and female (n = 10) SHRSP. When normalised to body weight there was no significant difference in the amount of PVAT surrounding the mesenteric arteries between male and female SHRSP (A). On histological analysis, adipocytes size was greater and adipocyte density lesser in the male SHRSP relative to the female SHRSP (B,C) (**p < 0.01; Student’s t-test). Representative histology sections of the PVAT adipocytes are shown in (D,E). Scale bar represents 50 μm.