Table 2 Characteristics of training and testing sets.

From: Deep learning-based survival prediction of oral cancer patients

  

Training set

Testing set

p-value

(n = 183)

(n = 72)

Sex

Female

63 (34.4%)

23 (31.9%)

0.818

Male

120 (65.6%)

49 (68.1%)

 

Age (mean(SD))

 

57.3 (12.6)

58.3 (11.0)

0.830

Site

Tongue

53 (29.0%)

20 (27.8%)

0.407

Mandibular gingiva

50 (27.3%)

12 (16.7%)

 

Maxillary gingiva

28 (15.3%)

12 (16.7%)

 

Buccal cheek

24 (13.1%)

12 (16.7%)

 

Retromolar trigone

17 (9.3%)

8 (11.1%)

 

Floor of mouth

10 (5.5%)

8 (11.1%)

 

Lip

1 (0.5%)

0 (0.0%)

 

Histologic grade

Well-differentiated

59 (32.2%)

13 (18.1%)

0.476

Moderately-differentiated

92 (50.3%)

52 (72.2%)

 

Poorly-differentiated

32 (17.5%)

7 (9.7%)

 

TNM Stage

I

50 (27.3%)

21 (29.2%)

0.995

II

37 (20.2%)

13 (18.1%)

 

III

14 (7.7%)

6 (8.3%)

 

IVA

70 (38.3%)

26 (36.1%)

 

IVB

12 (6.6%)

6 (8.3%)

 

T stage

T1

57 (31.1%)

22 (30.6%)

0.912

T2

47 (25.7%)

18 (25.0%)

 

T3

13 (7.1%)

9 (12.5%)

 

T4a

64 (35.0%)

22 (30.6%)

 

T4b

2 (1.1%)

1 (1.4%)

 

N stage

Nx

72 (39.3%)

33 (45.8%)

0.422

N0

13 (7.1%)

3 (4.2%)

 

N1

8 (4.4%)

4 (5.6%)

 

N2a

17 (9.3%)

6 (8.3%)

 

N2b

11 (6.0%)

6 (8.3%)

 

N3b

62 (33.9%)

20 (27.8%)

 

Bone marrow invasion

Absence

142 (77.6%)

55 (76.4%)

0.967

Presence

41 (22.4%)

17 (23.6%)

 

Perineural invasion

Absence

175 (95.6%)

65 (90.3%)

0.137

Presence

8 (4.4%)

7 (9.7%)

 

Lymphovascular permeation

Absence

174 (95.1%)

64 (88.9%)

0.094

Presence

9 (4.9%)

8 (11.1%)

 

Resection margin

Free from tumor

158 (86.3%)

61 (84.7%)

0.893

Presence of tumor

25 (13.7%)

11 (15.3%)

 

Extranodal extension

Absence

164 (89.6%)

62 (86.1%)

0.565

Presence

19 (10.4%)

10 (13.9%)

 

Postoperative RT

No

122 (66.7%)

47 (65.3%)

0.949

Yes

61 (33.3%)

25 (34.7%)

 

Postoperative CCRT

No

169 (92.3)

69 (95.8)

0.411

Yes

14 (7.7)

3 (4.2)

 

Overall Recurrence†

No

136 (74.3)

54 (75.0)

1.000

Yes

47 (25.7)

18 (25.0)

 

Cancer related death

No

150 (82.0)

61 (84.7)

0.734

Yes

33 (18.0)

11 (15.3)

 

Follow-up months (mean (sd))

 

79.7 (53.7)

82.3 (47.9)

0.448

  1. The entire dataset was split into two groups, 70% for training and 30% for testing. There were no statistically significant differences among the features of the two groups. Mann-Whitney U test for continuous variables; Chi square test, Fisher’s exact test, and Cochran-Armitage Trend test for categorical variables.
  2. RT = Radiation therapy, CCRT = Concurrent chemoradiotherapy.
  3. †Includes local recurrences and regional recurrences.
Back to article page