Figure 2
From: Bile-duct proliferation as an unexpected side-effect after AAV2-LDLR gene transfer to rabbit liver

Long-term follow-up of liver enzymes after AAV- and LV-mediated intraportal gene transfers. No significant changes were seen during long-term follow-up of liver enzymes after AAV2-LDLR (n = 5) and AAV2-control (n = 7) (a,d), AAV9-LDLR (n = 11) and AAV9-control (n = 6) (b,e) or LV-LDLR (n = 6) and LV-control (n = 4) (c,f) gene transfers into WHHL rabbit liver. Data is presented as mean ± SEM. Statistical significance was evaluated using Linear Mixed Models analysis (R statistical software, version 3.2.5).