Figure 1 | Scientific Reports

Figure 1

From: Acute-on-chronic liver disease enhances phenylephrine-induced endothelial nitric oxide release in rat mesenteric resistance arteries through enhanced PKA, PI3K/AKT and cGMP signalling pathways

Figure 1

Effect of microsurgical liver cholestasis (LC) on the concentration-dependent relaxation to acetylcholine (A) and on the concentration-dependent contraction to phenylephrine (B) in endothelium-intact rat mesenteric resistance segments. Results (mean ± S.E.M.) were expressed as a percentage of the initial contraction elicited by phenylephrine (A) or by KCl (B). n = 10 animals in each experimental group. *P < 0.05 (Bonferroni post-hoc test).

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