Figure 6 | Scientific Reports

Figure 6

From: Acute-on-chronic liver disease enhances phenylephrine-induced endothelial nitric oxide release in rat mesenteric resistance arteries through enhanced PKA, PI3K/AKT and cGMP signalling pathways

Figure 6

(A) Effect of microsurgical liver cholestasis (LC) on the concentration-dependent relaxation to NO donor DEA–NO in rat mesenteric resistance arteries. Influence of preincubation with the superoxide anion scavenger Tempol on mesenteric resistance arteries from Sham-Operated (SO, B) and LC rats. Results (mean ± S.E.M.) were expressed as a percentage of the initial contraction elicited by phenylephrine. n = 10 animals per experimental group. *P < 0.05 (Bonferroni post-hoc test).

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