Figure 8 | Scientific Reports

Figure 8

From: Acute-on-chronic liver disease enhances phenylephrine-induced endothelial nitric oxide release in rat mesenteric resistance arteries through enhanced PKA, PI3K/AKT and cGMP signalling pathways

Figure 8

Effect of microsurgical liver cholestasis (LC) on 6-Keto PGF1α release (A), TXB2 release (B). Results (mean ± S.E.M.) were expressed as pg prostanoid/mL mg tissue. (C) Vasoconstrictor-response to TXA2 receptor agonist U46619 in mesenteric resistance arteries from Sham-Operated (SO) and microsurgical liver cholestasis (LC) rats. Results (mean ± S.E.M.) were expressed as a percentage of the initial contraction elicited by KCl. n = 5–7 animals each experimental group. *P < 0.05 (Bonferroni post-hoc test).

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