Table 3 Effect of exposure to a depolarizing solution of KCl (120 mmol/L) in endothelium-intact (+E) and endothelium denuded (−E) mesenteric resistance segments from from sham-operated (SO) and microsurgical liver cholestasis (LC) rats.

From: Acute-on-chronic liver disease enhances phenylephrine-induced endothelial nitric oxide release in rat mesenteric resistance arteries through enhanced PKA, PI3K/AKT and cGMP signalling pathways

 

Contraction (mN)

+E

−E

SO

16.72 ± 0.92

13.75 ± 2.15

LC

15.78 ± 0.82

12.85 ± 1.96

  1. Results are expressed as means ± S.E.M. n = 10 animals each group.