Figure 3

Time to delivery in Camp−/− and wild type mice after intra-uterine PBS or LPS injection. Time to delivery of first pup after intra-uterine injection with PBS, 1 µg or 20 µg of LPS in cathelicidin-deficient mice (Camp−/−) and wild type (C57BL/6J) mice. Significance representing LPS treated mice compared to PBS controls from same genotype (*p < 0.05, **p < 0.01, ***p = 0.001), #p < 0.05 difference between genotype in the same treatment group, Two-way ANOVA). No symbol signifies no significant difference between the groups (p > 0.05). Preterm Birth (PTB) rates, defined as delivery before 24 hours rates in percentage are shown below. Significance is calculated by using Fisher’s Exact test.