Figure 4

IL-6, CXCL10 and TNF production in the maternal circulation after LPS injection. 6 hours after intrauterine injection with 1 µg LPS, PBS or no treatment at the same gestation. (a) Circulating interleukin-6 (IL-6) was significantly greater in the wild type mice (C57Bl/6J) (N = 6) compared to Camp−/− mice (N = 5, *p = 0.045) upon LPS treatment. (b, c) No significant differences were seen in CXCL10 or TNF production. Data presented as mean ± SD, Two-way ANOVA, Tukey’s multiple comparison test.