Figure 6

Bilateral asymmetry in early-stage KC. (A) Brillouin, corneal thickness and posterior elevation maps of the right and left eyes of a stage-I KC patient. Broken red circle indicates a 1-mm-radius cone region centered at the thinnest point. (B) Absolute difference in Brillouin frequency values between left and right eyes, measured at the corneal center for normal subjects (0.006 ± 0.004 GHz), the corneal center for stage-I KC patients (0.013 ± 0.007 GHz), and at the thinnest points for stage-I KC patients (0.024 ± 0.004 GHz). Normal subjects: n = 47, 39 ± 13 y/o, 51% female. Stage I KC patients: n = 4, 38 ± 5 y/o, 50% female. **p < 0.01, ***p < 0.001, by unpaired t-test.