Table 4 Inflammatory mediators and quality of life.
From: Systemic inflammation contributes to impairment of quality of life in chronic pancreatitis
Predictive Variable | Questionnaire | Quality of Life Domain(s) | Mean Score (Low) | Mean Score (High) | Bonferroni p-value |
|---|---|---|---|---|---|
Eotaxin | PAN-28 | Bowel Function | 24.5 | 34.9 | 0.03 |
Abdominal Bloating | 54.6 | 37.6 | 0.009 | ||
IL-7 | QLQ-C30 | Global Quality of Life | 55.8 | 48.2 | 0.04 |
Fatigue | 43.5 | 53.1 | 0.03 | ||
Nausea and Vomiting | 20.0 | 29.8 | 0.03 | ||
Dyspnoea | 19.3 | 30.4 | 0.01 | ||
Diarrhoea | 17.2 | 27.4 | 0.01 | ||
IL-8 | QLQ-C30 | Global Quality of Life | 56.0 | 48.3 | 0.04 |
Physical Functioning | 78.9 | 67.8 | 0.002 | ||
Cognitive Functioning | 77.5 | 68.3 | 0.02 | ||
Nausea and Vomiting | 20.0 | 29.4 | 0.04 | ||
Dyspnoea | 20.1 | 29.1 | 0.05 | ||
Appetite Loss | 32.6 | 44.0 | 0.03 | ||
IL-12/IL-23p40 | QLQ-C30 | Dyspnoea | 29.6 | 29.5 | 0.03 |
IL-16 | QLQ-C30 | Global Quality of Life | 56.7 | 47.5 | 0.01 |
Physical Functioning | 78.4 | 68.2 | 0.005 | ||
Cognitive Functioning | 77.5 | 68.1 | 0.02 | ||
Fatigue | 43.0 | 53.3 | 0.02 | ||
Nausea and Vomiting | 17.2 | 32.3 | 0.001 | ||
Dyspnoea | 19.2 | 30.1 | 0.02 | ||
IP-10 | QLQ-C30 | Dyspnoea | 20.2 | 29.3 | 0.04 |
PAN-28 | Bowel Function | 19.7 | 38.3 | <0.0001 | |
MCP-4 | PAN-28 | Bowel Function | 23.8 | 34.8 | 0.02 |
MDC | QLQ-C30 | Physical Functioning | 78.7 | 67.8 | 0.003 |
Fatigue | 43.1 | 53.3 | 0.02 | ||
Nausea and Vomiting | 17.2 | 32.4 | 0.001 | ||
Dyspnoea | 17.9 | 31.5 | 0.002 | ||
Bowel Function | 22.0 | 36.1 | 0.002 | ||
Weight Loss | 24.2 | 39.9 | 0.02 | ||
MIP-1a | QLQ-C30 | Global Quality of Life | 56.5 | 47.6 | 0.02 |
Physical Functioning | 80.2 | 66.2 | <0.0001 | ||
Cognitive Functioning | 78.3 | 67.2 | 0.004 | ||
Fatigue | 40.9 | 55.6 | 0.001 | ||
Nausea and Vomiting | 17.6 | 32.1 | 0.001 | ||
Dyspnoea | 18.6 | 30.8 | 0.007 |
