Table 2 The effect of regular exercise on circulating microRNAs related to cardiovascular disease.

From: The Effects of Regular Exercise on Circulating Cardiovascular-related MicroRNAs

miRNA

n

Fold-Change (SD)

P value a

q value b

miR-486-5p

20

0.65 (0.4)

0.0002

0.0009

let-7b-5p

20

0.64 (0.5)

0.0003

0.0019

miR-142-3p

19

3.60 (3.8)

0.001

0.0028

miR-221-3p

19

2.70 (2.6)

0.0015

0.0038

miR-29c-3p

20

0.77 (0.3)

0.0015

0.0047

miR-126-3p

20

1.41 (0.5)

0.0025

0.0057

let-7e-5p

18

0.65 (0.4)

0.004

0.0066

miR-93-5p

18

0.73 (0.5)

0.0049

0.0075

miR-7-5p

16

0.75 (1.3)

0.0052

0.0085

miR-146a-5p

20

1.55 (0.8)

0.0053

0.0094

miR-25-3p

20

0.78 (0.4)

0.0053

0.0104

miR-27b-3p

20

1.97 (1.2)

0.0062

0.0113

miR-92a-3p

20

0.83 (0.4)

0.0098

0.0123

miR-29b-3p

16

0.79 (0.4)

0.0131

0.0132

let-7d-5p

20

0.84 (0.4)

0.0175

0.0142

miR-17-5p

16

2.04 (1.7)

0.0208

0.0151

miR-424-5p

19

1.85 (1.5)

0.0439

0.016

miR-23a-3p

20

1.35 (0.6)

0.0477

0.017

miR-222-3p

18

1.36 (0.6)

0.0483

0.0179

miR-30c-5p

20

1.62 (0.9)

0.0579

0.0189

miR-27a-3p

20

2.04 (1.6)

0.0613

0.0198

miR-103a-3p

13

7.42 (12.3)

0.079

0.0208

let-7a-5p

20

1.06 (1.1)

0.0875

0.0217

miR-29a-3p

20

1.50 (1.0)

0.0907

0.0226

miR-24-3p

20

1.47 (0.7)

0.0917

0.0236

miR-125a-5p

20

1.46 (0.9)

0.1006

0.0245

miR-16-5p

20

1.01 (1.0)

0.1025

0.0255

let-7c

20

1.11 (1.2)

0.1324

0.0264

miR-342-3p

20

1.47 (1.0)

0.1514

0.0274

miR-15b-5p

20

0.95 (0.4)

0.1564

0.0283

miR-181b-5p

14

1.67 (1.4)

0.2046

0.0292

miR-224-5p

10

2.37 (2.2)

0.2192

0.0302

miR-125b-5p

15

2.57 (2.9)

0.2577

0.0311

miR-130a-3p

11

2.20 (1.7)

0.3041

0.0321

miR-195-5p

20

1.48 (2.5)

0.3096

0.033

miR-185-5p

18

1.60 (2.1)

0.3166

0.034

miR-10b-5p

14

3.42 (4.3)

0.3411

0.0349

miR-150-5p

20

1.40 (0.8)

0.3693

0.0358

miR-23b-3p

19

1.34 (0.6)

0.4056

0.0368

miR-223-3p

20

1.37 (1.3)

0.4779

0.0377

miR-320a

20

1.13 (1.0)

0.5106

0.0387

miR-30e-5p

18

1.72 (2.1)

0.6095

0.0396

miR-423-3p

13

2.21 (2.3)

0.6245

0.0406

miR-98-5p

18

1.31 (0.9)

0.6554

0.0415

miR-26a-5p

20

1.11 (0.5)

0.7655

0.0425

miR-122-5p

20

1.41 (1.4)

0.7881

0.0434

miR-26b-5p

19

3.97 (13.1)

0.82

0.0443

miR-451a

20

1.89 (2.9)

0.8475

0.0453

miR-100-5p

19

1.59 (1.6)

0.8936

0.0462

miR-30d-5p

20

1.30 (1.1)

0.9146

0.0472

miR-30a-5p

20

1.31 (1.0)

0.9536

0.0481

miR-21-5p

20

1.06 (0.4)

0.9546

0.0491

miR-365a-3p

15

1.65 (1.8)

0.9907

0.05

  1. n represents the number of subjects in which the miRNA was detectable in both baseline and post-training samples.
  2. aP values are the result of paired t-tests of normalized baseline and post-training miRNA expression levels.
  3. bWhen P < q the change in expression with training is deemed significant, which is indicated in bold.
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