Figure 1 | Scientific Reports

Figure 1

From: Effect of mycalolides isolated from a marine sponge Mycale aff. nullarosette on actin in living cells

Figure 1

The initial screening using a cell-based assay. (A) The scheme for the screening. MDA-MB-231 cells were grown for 20 hr in the presence or absence of 10 μg/ml alcoholic extracts from marine organisms. The cells were fixed, and stained with Hoechst 33342. (B) Formation of binucleated cells. Arrows indicate the binucleated cells observed in 10 μg/ml crude extract of marine sponge Mycale aff. nullarosette. The arrows indicate the cells harboring two daughter nuclei. Bar, 100 μm.

Back to article page