Figure 3
From: High fidelity fibre-based physiological sensing deep in tissue
Sensor fabrication. (A) Brightfield image of 10 µm amino functionalised silica microspheres. (B) (i) pH sensor: 5(6)-Carboxyfluorescein (FAM) and 5(6)-Carboxytetramethylrhodamine (TAMRA) covalently coupled onto the silica microspheres (not representative of loading ratio). (ii) Oxygen sensor: palladium(II) 5,10,15,20-meso-tetrakis-(2,3,4,5,6-pentafluorophenyl)-porphyrin (PdTFPP) covalently coupled onto the silica microspheres. (C) The structures of: (i) FAM and TAMRA and (ii) PdTFPP for conjugation onto the silica microspheres.
