Figure 5

Close view of the amphipathic pocket surrounding the tryptophan undergoing mutation to arginine in YafQ_rh2360. (a) E. coli YafQ (PDB ID: 4ml2). (b) Homology model of YafQ_rh2360. (c) Homology model of YafQ_rh2360R. In all close views the tryptophan and the arginine are shown in sticks, hydrophobic residues are shown in light grey space-fill while charged and polar residues are in colour.