Table 1 Central composite circumscribed (CCC) design with five levels and three variables for phenolic compound extraction in D. indicum var. aromaticum flower and observed responsesa.

From: An Optimized Method for Extraction and Characterization of Phenolic Compounds in Dendranthema indicum var. aromaticum Flower

Run order

Independent variables

TP content (g GAEb/100 g DW)

Coded

Uncoded

Time (min)

Solid/liquid ratio (g/mL)

Temperature (°C)

Time (min)

Solid/liquid ratio (g/mL)

Temperature (°C)

1

−1

−1

−1

20

1:10

40

0.71

2

1

−1

−1

40

1:10

40

0.93

3

−1

1

−1

20

1:30

40

1.16

4

1

1

−1

40

1:30

40

1.04

5

−1

−1

1

20

1:10

60

0.84

6

1

−1

1

40

1:10

60

1.03

7

−1

1

1

20

1:30

60

1.27

8

1

1

1

40

1:30

60

1.21

9

−1.68

0

0

13

1:20

50

1.11

10

1.68

0

0

47

1:20

50

1.28

11

0

−1.68

0

30

1:03

50

0.68

12

0

1.68

0

30

1:37

50

1.23

13

0

0

−1.68

30

1:20

33

0.89

14

0

0

1.68

30

1:20

67

1.13

15

0

0

0

30

1:20

50

1.02

16

0

0

0

30

1:20

50

1.20

17

0

0

0

30

1:20

50

1.07

18

0

0

0

30

1:20

50

1.26

19

0

0

0

30

1:20

50

1.15

20

0

0

0

30

1:20

50

1.07

  1. aExperimental results for TP content are mean value of triplicates.
  2. bGallic acid equivalent.