Table 8 Comparison of mutations between HIV-1 seronegative and seropositive individuals.

From: Genetic Polymorphisms in the Open Reading Frame of the CCR5 gene From HIV-1 Seronegative and Seropositive Individuals From National Capital Regions of India

Mutations

HIV-1 negative

HIV-1 positive

p-value (Chi-square test)

q-value (post Benjamini-Hochberg multiple testing correction)

Total number of individuals carrying the mutation

Total individuals (n)

Total number of individuals carrying the mutation

Total individuals (n)

S38L*

4

70

0

72

0.0396

0.1727

L55P*

4

70

0

72

0.0396

0.1727

H181S*

4

70

0

72

0.0396

0.1727

Q194H*

4

70

0

72

0.0396

0.1727

R319H*

4

70

0

72

0.0396

0.1727

FS at 156*

4

70

0

72

0.0396

0.1727

FS at 220*

4

70

0

72

0.0396

0.1727

F41L*

0

70

4

72

0.0396

0.1727

A73P*

0

70

4

72

0.0396

0.1727

W86G*

0

70

6

72

0.0136

0.1727

R88H*

0

70

4

72

0.0396

0.1727

A90P*

0

70

5

72

0.0248

0.1727

G97E*

0

70

4

72

0.0396

0.1727

F107L*

0

70

6

72

0.0136

0.1727

W153R*

0

70

4

72

0.0396

0.1727

  1. Abbreviations:
  2. C-Conserved; NC- Non-Conserved;
  3. NR- Not Reported FS-Frame-shift;
  4. *-Found in our study; X-Stop Codon;
  5. Δ-Deletion;Insert-Insertion.
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