Figure 3 | Scientific Reports

Figure 3

From: Establishment and genomic characterization of gingivobuccal carcinoma cell lines with smokeless tobacco associated genetic alterations and oncogenic PIK3CA mutation

Figure 3

Chromosomal analysis of OSCC cell lines. (A) Composite karyotype of ITOC-01 cell line: 63 70,XY, +der(1)(p36), +der(2)t(2;6)(p24;q13), +der(3)del(3)(p10)x2,4, +5, +6,dup(7)(q11.2q22), +der(7)t(4;7)(q21;p22),del(7)(q32), +9, +der(9)t(9;?13)(p23;?q10), +10, +10, +der(11)t(4;11)(pterq26;p15),add(12)(p13), +13, +14, +14,der(14)t(13;14)(q10;q10), +15, +der(15)add(15)(p11.5), +16, +17,der(18)dup(18)(q21.1;q23), +20, +20,der(21)t(21;?)(q21;?),add(21)(q21)[cp20]. (B) Composite karyotype of ITOC-02 cell line: 72 82,XX, +1, +3, +5, +8, +8, +9, +9,i(9)(q10;q10), +11, +11, +der(11)dup(11)(q13q23), +der(11)?t(11;?)(q;?),der(13)t(13;14)(q10;q10)x2, +der(13)t(13;?)(q10;?), +14, +14, +15, +der(15)t(14;15)(q10;q10)x3, +16, +16, +16, +17, +18, +18, +der(18)t(11;18)(q23;q23),19, +20, +20, +, +der(21)t(17;21)(q21;q22),der(21)t(21;21)(q10;q22)x3, +mar[cp20]. (C) Composite karyotype of ITOC-03 cell line: 80 89,XY, +X, +1, +2, +3, +3, +4, +5, +der(6)t(6;?)(q10;?), +7, +7, +8, +9, +10, +11, +11, +12, +12, +der(13),t(13;14)(q10;q10)x2, +der(13)t(13;13)(q10;q10)x3, +14, +, +14, +der(14)add(14)(q11.2), +15, +15, +der(15)t(15;?)(q11.2;?)x2, +16, +16, +17, +17, +18, +19, +20, +20, +mar x3[cp20]. (D) Composite karyotype of ITOC-04 cell line: 84 93,X,der(1)dup(1)(q22p33); +der(2)add(2)(p22p23), +der(3)t(3;?)(p21;?)x2, +4, +5, +5, +6, +7, +7, +8, +9, +9,i(9)(q10;q10), +der(10)t(10;?)(p10;?),der(11)dup(11)(q23)x3, +12, +12, +13, +15, +15,der(15)dup(15)(p10), +16, +17,18, +20, +20, +20, +21, +21, +21, +21, +der(21)t(21;21)(q10;q10), +22, +22, +mar1, +mar2x2, +mar3[cp20].

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