Figure 4

Tumourigenicity of OSCC cell lines. (A–D) Subcutaneous tumor formation in nude (ITOC-01) and NOD SCID mice (ITOC-02, ITOC-03, ITOC-04) after inoculation of OSCC cell lines. (E–H) Micro PET images of 18-FDG uptake in coronal planes for cell line xenografted mice. Tumor is indicated with white broken line with areas of necrosis depicted with *. Blue arrow indicates the viable base tumor in PET scan. (I–L) (H&E) stained microphotographs from tumor xenografts captured at 10X magnification.