Table 1 Patient’s demographic, tumour and treatment characteristics.
ITOC-01 | ITOC-02 | ITOC-03 | ITOC-04 | |
|---|---|---|---|---|
Patient age, Gender & Ethnicity | 28 years, Male, Indian | 43 years, Female, Indian | 37 years, Male, Indian | 61 years, Male, Indian |
Primary site | Buccal mucosa | Oral tongue | Buccal mucosa | Buccal mucosa |
Histology (grade) | SCC (poorly differentiated) | SCC (poorly differentiated) | SCC (moderately differentiated) | SCC (poorly differentiated) |
Pathological staging | T4N2cM0 | T4aN0 | T3N2bM0 | T4aN2bM0 |
Habits | Chronic tobacco chewer using Gutka, Masheri, Paan with tobacco & Snuff. No smoking or alcohol. | Chronic tobacco chewer using Masheri. No smoking or alcohol. | Chronic tobacco chewer. No smoking or alcohol. | Chronic tobacco chewer using Gutka. No smoking or alcohol. |
Treatment details | Radical surgery followed by radiotherapy (RT) + chemotherapy (CT) | Radical surgery followed by RT + CT | Radical surgery followed by RT + CT | Neoadjuvant Paclitaxel and Carboplatin chemotherapy followed by radical surgery. Subsequent adjuvant RT + CT |
Treatment outcome | Rapid progression and died after 6 months | Rapid progression after 6 months of treatment | Disease controlled at 1 year follow up | Disease controlled at 6 month follow up |