Table 3 Predictors of AF development by Multivariate Cox regression Analysis. Model 1 was adjusted for sex and age; model 2 included GFR and model 3 also LVH and carotid plaque.

From: CHA2DS2-VASc score and left atrial volume dilatation synergistically predict incident atrial fibrillation in hypertension: an observational study from the Campania Salute Network registry

Variable

Model 1

Model 2

Model 3

p

HR (95%Cl)

p

HR (95%Cl)

p

HR (95%Cl)

High CHA2-DS2-VASC and Normal LAVI

<0.0001

2.99 (1.64–5.43)

0.001

2.77 (1.50–5.12)

0.002

2.63 (1.41–4.89)

Low CHA2-DS2-VASC and Dilated LAVI

0.003

2.41 (1.35–4.29)

0.004

2.36 (1.33–4.21)

0.012

2.13 (1.18–3.85)

High CHA2-DS2-VASC and Dilated LAVI

<0.0001

8.54 (5.14–14.19)

<0.0001

7.74 (4.51–13.27)

<0.0001

6.57 (3.70–11.65)

GFR (ml/m/m21.73)

  

0.291

0.99 (0.98–1.01)

0.384

0.99 (0.98–1.01)

LVH

    

0.106

1.39 (0.93–2.08)

Carotid Plaque

    

0.815

1.05 (0.71–1.54)

  1. GFR = glomerular filtration rate; LAVI: left atrial volume index; LVH: left ventricular hypertrophy.
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