Figure 6
From: Nerve sprouting capacity in a pharmacologically induced mouse model of spinal muscular atrophy
Slight but statistically significant reduction of tSCs/NMJ area in pharmacological SMA SOL. Number of tSCs per NMJ (A), NMJ AChR area (B) and tSC normalized to NMJ area (C) on non-denervated, contralateral muscles. Sample sizes: DMSO WT: 6 mice, 78 NMJs (A) 55 NMJs (B,C). LD SMA: 5 mice, 92 NMJs (A) 62 NMJs (B,C). HD SMA: 5 mice, 122 NMJs (A) 76 NMJs (B,C). ANOVA yielded p = 0.0301 for tSC/NMJ area but pairwise Bonferroni comparisons between groups were not significant.
