Table 2 Baseline characteristics of AP patients according to ApoB/A1 ratio quartiles.

From: Serum apolipoprotein B-to-apolipoprotein A1 ratio is independently associated with disease severity in patients with acute pancreatitis

Characteristics

Quartile 1 (0.19–0.60)

Quartile 2 (0.61–0.80)

Quartile 3 (0.81–0.98)

Quartile 4 (0.99–1.67)

P

No. of patients

94

93

94

94

 

SAP, n (%)

5 (5.3)

12 (12.9)

20 (21.3)

28 (29.8)

<0.001

Age, year

52.18 ± 14.31

51.72 ± 14.15

53.25 ± 15.57

53.59 ± 15.63

0.743

Male sex, n (%)

55 (58.5)

56 (60.2)

59 (62.8)

60 (63.8)

0.875a

Etiology, n (%)

    

0.197a

   Gallstones

62 (66.0)

66 (71.0)

69 (73.4)

75 (79.8)

 

   Other

32 (34.0)

27 (29.0)

25 (26.6)

19 (20.2)

 

BMI, kg/m2

23.41 ± 3.02

23.85 ± 3.24

24.57 ± 3.95

25.13 ± 4.36

0.008

Smoking habit, n (%)

24 (25.5)

27 (29.0)

31 (33.0)

35 (37.2)

0.342a

WBC count, ×109/L

11.77 ± 4.52

12.48 ± 5.17

12.89 ± 5.33

13.42 ± 5.68

0.169

Neutrophil count, ×109/L

9.08 ± 3.66

10.37 ± 4.05

11.94 ± 4.55

13.56 ± 6.10

<0.001

Lymphocyte count, ×109/L

1.08 ± 0.64

1.11 ± 0.67

1.04 ± 0.61

1.01 ± 0.62

0.719

RBC count, ×109/L

4.79 ± 0.73

4.68 ± 0.71

4.66 ± 0.71

4.55 ± 0.68

0.144

HGB, g/L

141.27 ± 26.48

145.23 ± 27.36

139.84 ± 24.99

140.77 ± 25.23

0.512

PLT, ×109/L

186.54 ± 60.66

180.55 ± 67.48

177.97 ± 64.24

173.59 ± 61.15

0.562

CRP, mg/L

76 (19–124)

125 (81–234)

171 (123–288)

222 (145–381)

<0.001 c

ALT, U/L

101 (6–754)

99 (8–821)

105 (15–972)

116 (12–1061)

0.492c

AST, U/L

121 (15–831)

129 (25–874)

132 (20–968)

130 (18–912)

0.740c

LDH, U/L

267.06 ± 148.42

316.63 ± 158.71

391.14 ± 172.45

469.89 ± 211.31

<0.001

Glucose, mmol/L

7.72 ± 3.65

8.55 ± 4.79

8.26 ± 4.67

9.33 ± 4.54

0.093

ALB, g/L

37.76 ± 6.42

36.24 ± 5.85

34.89 ± 5.33

32.63 ± 5.35

<0.001

Amylase, U/L

525 (50–2907)

671 (81–3233)

797 (74–3452)

875 (88–3666)

<0.001 c

BUN, mmol/L

4.35 ± 1.37

4.77 ± 1.52

5.16 ± 1.81

6.13 ± 2.99

<0.001

Calcium, mmol/L

2.13 ± 0.28

2.10 ± 0.25

2.07 ± 0.24

2.06 ± 0.26

0.239

TC, mmol/L

3.84 ± 1.88

4.03 ± 2.10

3.97 ± 2.06

4.12 ± 2.20

0.822

TG, mmol/L

2.84 ± 1.72

3.25 ± 1.92

3.69 ± 2.68

4.21 ± 2.98

<0.001

HDL-C, mmol/L

1.27 ± 0.32

1.22 ± 0.27

1.20 ± 0.25

1.16 ± 0.24

0.048

LDL-C, mmol/L

2.71 ± 1.33

2.95 ± 1.51

3.14 ± 1.54

3.39 ± 1.91

0.027

ApoA1, g/L

1.24 ± 0.55

1.18 ± 0.52

1.07 ± 0.45

0.93 ± 0.40

<0.001

ApoB, g/L

0.68 ± 0.47

0.79 ± 0.49

0.88 ± 0.57

0.98 ± 0.62

0.002

APACHE II score (at 24 h)

3.0 (2.0–6.0)

6.0 (3.0–10.0)

10.0 (6.0–15.0)

13.0 (8.0–19.0)

<0.001 c

Ranson score (at 48 h)

2.0 (1.0–2.0)

2.0 (1.0–2.0)

4.0 (1.0–5.0)

5.0 (3.0–7.0)

<0.001 c

BISAP score

1.0 (0.0–1.0)

1.0 (0.0–2.0)

2.0 (1.0–2.0)

2.5 (1.0–3.0)

<0.001 c

CTSI score

2 (1–3)

4 (1–6)

5 (2–7)

6 (3–8)

<0.001 c

Hospital stay, days

7 (5–11)

13 (8–27)

26 (14–40)

45 (20–68)

<0.001 c

Intensive care unit, n (%)

11 (11.7)

18 (19.4)

34 (36.2)

45 (47.9)

<0.001 a

28 days mortality, n (%)

0 (0.0)

0 (0.0)

2 (2.1)

5 (5.3)

0.019 b

  1. Continuous variables are described as means ± standard deviation (normal distribution) or median and interquartile range (abnormal distribution). Categorical variables are described as N (%).
  2. aStatistical results based on χ2 analysis; bStatistical results based on Fisher’s exact test; cStatistical results based on Kruskall-Wallis test; the others were based on one way variance analysis.
  3. SAP, severe acute pancreatitis; BMI, body mass index; WBC, white blood cell; RBC, red blood cell; HGB, hemoglobin; PLT,platelets; CRP, C-reactive protein; ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactate dehydrogenase; ALB, albumin; BUN, blood urea nitrogen; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low -density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; ApoB/A1 ratio, apolipoprotein B-to-apolipoprotein A1 ratio; APACHE II, acute physiology and chronic health evaluationII; BISAP, besides index for severity in acute pancreatitis; CTSI, CT severity index.
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