Figure 8 | Scientific Reports

Figure 8

From: Exploiting chitosan and gold nanoparticles for antimycobacterial activity of in silico identified antimicrobial motif of human neutrophil peptide-1

Figure 8

Evaluation of safety profile of Pep-H loaded nanoformulations against MDMs. (a) Percentage cell viability of MDMs upon treatment with different concentrations of Pep-H and its nanoformulations. (b) Percent cytotoxicity of Pep-H and its nanoformulations at different concentrations in MDMs. The cells were treated with various concentrations of Pep-H as well as Pep-H-CSNPs and Pep-H-AuNPs respectively for 72 hrs. The effect of this treatment on cell viability was assessed by MTT assay. The supernatants of these treated cells were subjected to LDH assay to determine cytotoxicity of free peptides and their nanoparticle formulations. Values are expressed as Mean ± S.D. of 3 independent experiments.

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