Table 1 KEGG pathways with significant enriched up-regulated transcripts and proteins.

From: Variable protein homeostasis in housekeeping and non-housekeeping pathways under mycotoxins stress

Toxin

KEGG pathway (transcriptome)

P value

KEGG pathway (proteome)

P value

AFB1

Cytokine-cytokine receptor interaction

0.02

Fructose and mannose metabolism

0.00013

 

Intestinal immune network for IgA production

0.001739

Retinol metabolism

0.000283

 

Jak-STAT signaling pathway

0.003656

Chemical carcinogenesis

0.002798

 

Glycosaminoglycan biosynthesis - chondroitin sulfate/dermatan sulfate

0.003893

Biosynthesis of amino acids

0.004614

 

ECM-receptor interaction

0.007142

  
 

Phagosome

0.007149

  
 

Cell adhesion molecules (CAMs)

0.008871

  

OTA

  

Complement and coagulation cascades

0.000614

ZEN

Cell cycle

2.72E-12

Biosynthesis of amino acids

0.001971

 

DNA replication

6.67E-11

  
 

Fanconi anemia pathway

5.08E-09

  
 

Ribosome biogenesis in eukaryotes

4.35E-08

  
 

Pyrimidine metabolism

9.56E-08

  
 

Spliceosome

6.70E-07

  
 

RNA transport

1.06E-06

  
 

Mismatch repair

8.52E-06

  
 

Homologous recombination

9.64E-06

  
 

Nucleotide excision repair

0.00104

  
 

Base excision repair

0.001211

  
 

RNA polymerase

0.001602

  
 

mRNA surveillance pathway

0.002268

  
 

Purine metabolism

0.005707

  
 

p53 signaling pathway

0.008001

  
  1. P value is calculated by Fisher’s exact test with FDR correction.