Figure 5

[18F]FDG-Uptake in LN18 (A) and EJ28Luc (B) cells treated with 213Bi-anti-EGFR-MAb. The diagrams show the uptake following a 90 min incubation with [18F]FDG of cells (three replicates) treated with 213Bi-anti-EGFR-MAb or mock-treated with PBS (control). In both cell lines 213Bi-anti-EGFR-MAb induced a decrease in [18F]FDG uptake. The decrease was statistically significant in EJ28 cells (p = 0.0095) and showed a trend towards statistical significance in LN18 cells (p = 0.054). Displayed are mean ± SD.