Figure 6 | Scientific Reports

Figure 6

From: Opposing effects of acute versus chronic inhibition of p53 on decitabine’s efficacy in myeloid neoplasms

Figure 6The alternative text for this image may have been generated using AI.

Effects of acute and chronic p53 depletion on expression of p53 target genes in MLL-AF9 leukemia cells. Quantitative PCR of relative mRNA levels for several p53 target genes in MLL-AF9 cells with indicated p53 modulations. Cells were treated with DMSO or decitabine (50 nM) for 24 hours. Results were normalized to Gapdh, with the relative mRNA level in NT-transduced control cells was set to 1. Data are shown as mean ± s.d. of duplicate wells.

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