Table 2 The electrotaxis in MRC-5, H460 and H520 cells without and with doxycycline.

From: Doxycycline inhibits electric field-induced migration of non-small cell lung cancer (NSCLC) cells

Groups

Cell number

Directedness (Σcosθ/n) ± SEM

Migration speed (μm/h) ± SEM

6 h

p a

p b

6 h

p a

p b

MRC5-CTL

103

−0.04 ± 0.07

***

 

12.08 ± 1.02

**

 

MRC5-EF

100

−0.39 ± 0.06

***

5.61 ± 0.59

**

H460-CTL

105

0.06 ± 0.07

***

 

0.79 ± 0.05

***

 

H460-EF

112

0.87 ± 0.02

***

***

1.96 ± 0.20

***

***

H520-CTL

97

0.08 ± 0.08

***

 

0.53 ± 0.05

***

 

H520-EF

115

0.81 ± 0.03

***

***

1.24 ± 0.09

***

***

Dox-MRC5-CTL

161

−0.09 ± 0.05

 

5.88 ± 0.29

 

Dox-MRC5-EF

122

−0.24 ± 0.06

6.08 ± 0.35

Dox-H460-CTL

112

−0.10 ± 0.05

 

0.78 ± 0.07

 

Dox-H460-EF

160

−0.05 ± 0.06

***

0.90 ± 0.06

***

Dox-H520-CTL

389

0.08 ± 0.04

***

 

0.75 ± 0.04

 

Dox-H520-EF

391

0.27 ± 0.04

***

***

0.76 ± 0.03

***

  1. pa, p value of independent t-test between CTL and EF.
  2. pb, p value of independent t-test between EF and Dox-EF.
  3. , no significant; *p < 0.05; **p < 0.01; ***p < 0.001. SEM, standard error of the mean.