Figure 3 | Scientific Reports

Figure 3

From: Automated detection of the HER2 gene amplification status in Fluorescence in situ hybridization images for the diagnostics of cancer tissues

Figure 3

Comparison of the accuracy of nucleus detector and signal detector on the image-wide nucleus detection and classification. (A) The accuracy in classifying the detected nuclei was compared among the 57 validation FISH images. Exemplarily, the four most interesting images are depicted where (1) the accuracy was nearly 100% in both steps (image 35), (2) the accuracy was low in both steps (image 25), (3) nucleus detector had a better accuracy than signal detector (image 8) or (4) vice versa (image 14). (B) Detailed overview about the classification of the nuclei in these four FISH images and (C) visualization of the classification of nucleus detector. Nuclei with a differing classification by signal detector are marked with a red arrow.

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