Table 1 Clinical characteristics of liver transplant recipients categorized by D-MELD.

From: Pre-Operative Delta-MELD is an Independent Predictor of Higher Mortality following Liver Transplantation

 

Total Cohort (n = 12,785)

D-MELD 0–4 (n = 8,862)

D-MELD 5–10 (n = 2,574)

D-MELD > 10 (n = 1,529)

P value

Median Age (IQR)

55 (48–61)

55 (48–61)

56 (49–62)

57(50–62)

0.1528

Male, (%)

8239 (64.4)

5726 (64.6)

1591 (61.8)

922(60.3)

0.3372

Ethnicity, (%)

Caucasian

9058 (70.8)

6180 (71.2)

1830 (71.1)

1048 (68.5)

0.0029

Black

1363 (10.7)

1002 (11.5)

246 (9.6)

115 (7.5%)

Hispanic

1833 (14.3)

1153 (13.3)

386 (15.0)

294 (19.2)

Asian

352 (2.8)

230 (2.6)

74 (2.9)

48 (3.1)

Etiology of Liver Disease, (%)

ALD

2885 (22.6)

2109 (24.3)

520 (20.2)

256 (16.7)

0.0002

HCV

3076 (24.1)

1994 (22.5)

632 (24.6)

450 (29.4)

ALD/HCV

652 (5.1)

442 (5.1)

121 (4.7)

89 (5.8)

NASH

1941 (15.2)

1342 (15.5)

397 (15.4)

202 (13.2)

Cholestatic Liver Disease

1342 (10.5)

851 (9.8)

292 (11.3)

199 (13.0)

Other

2889 (22.6)

1944 (22.4)

612 (23.8)

333 (21.8)

Median Liver Donor Risk Index (IQR)

1.36 (1.12, 1.65)

1.36 (1.12, 1.65)

1.35 (1.12, 1.62)

1.34 (1.13, 1.63)

0.8350

Donation after Cardiac Death, (%)

588 (4.6)

442 (5.3)

104 (4.1)

42 (2.8)

0.0258

Renal Dialysis, (%)

3652 (28.6)

2300 (26.5)

639 (24.8)

713 (46.6)

<0.0001

Ascites, (%)

11151 (87.2)

7489 (86.3)

2263 (87.9)

1399 (91.5)

0.0004

Severe Hepatic Encephalopathy, (%)

2052 (16.1)

1234 (14.2)

455 (17.7)

363 (23.7)

<0.0001

  1. ALD, alcoholic liver disease, D-MELD, delta change in Model for End-Stage Liver Disease score; HCV, chronic hepatitis C virus infection; INR, international normalized ratio for prothrombin time; IQR, interquartile range; NASH, nonalcoholic steatohepatitis.