Figure 1
LN urinary biomarker, chemokine, cytokine and growth factor secretion after 24-hour ciGEnC-stimulation with individual cytokines, combination of all cytokines (All) and LPS. MCP-1 (a), sVCAM-1 (b), IL-6 (c), IL-8 (d), IL-10 (e), M-CSF (f), GM-CSF (g), MIP-1α (h), IP-10 (i), TNF-α (j) and IFN-γ (k) secretion in response to cytokine treatments. MCP-1 (l) and M-CSF secretion (m) following combined TNF-α and IL-1β treatments. N = 5–6/group, Data are presented as median concentrations (pg/ml) [range] are analysed using Kruskal-Wallis test with Dunn’s post-hoc test, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs untreated.
