Table 3 Brain regions that exhibited significant positive correlations between empathizing and MD.

From: Empathizing associates with mean diffusivity

Included gray matter areas* (number of significant voxels in the left and right side of each anatomical area)

Included large bundles** (number of significant voxels in the left and right side of each anatomical area)

x

y

z

TFCE value

Corrected p value (FWE)

Cluster size (voxel)

r***

Anterior cingulum (L:1)/Middle cingulum (L:185)/Inferior frontal operculum (L:10)/Inferior frontal triangular (L:64)/Middle frontal other areas (L:848)/Superior frontal medial area (L:76)/Superior frontal other areas (L:647)/Insula (L:6)/Precentral gyrus (L:137)/Supplemental motor area (L:763)/

Body of corpus callosum (1)/Anterior corona radiata (L:169)/Superior corona radiata (L:534)/Superior longitudinal fasciculus (L:79)/

−22.5

7.5

42

1764

0.004

6091

0.102

Postcentral gyrus (L:56)/Rolandic operculum (L:123)/

Superior longitudinal fasciculus (L:3)/

−49.5

−10.5

15

944

0.0442

172

0.093

Middle cingulum (L:1)/

None

−4.5

22.5

37.5

917

0.0486

1

0.055

  1. *Labelings of the anatomical regions of gray matter were based on the WFU PickAtlas Tool (http://www.fmri.wfubmc.edu/cms/software#PickAtlas/)70,71 and on the PickAtlas automated anatomical labeling atlas option72. Temporal pole areas included all subregions in the areas of this atlas.
  2. **The anatomical labels and significant clusters of major white matter fibers were determined using the ICBM DTI-81 Atlas (http://www.loni.ucla.edu/).
  3. ***Simple correlation coefficients between the mean values of the significant clusters and those of the empathizing score. Note that due to whole-brain analyzes overfitting69, the correlation coefficients of significant areas are overestimated to a degree dependent on the sample size and number of comparisons.
Back to article page