Figure 1
From: Combating viral contaminants in CHO cells by engineering innate immunity
RNA viruses induce cytopathic effects on CHO-K1 cells. (A) Cytopathic effect of the three RNA viruses on CHO cells upon 30 h (VSV), 54 h (EMCV) or 78 h (Reo-3) of infection. Fold change in IFNβ (B) and Mx1 (C) gene expressions in CHO cells infected with the three RNA viruses compared to uninfected cells at the same time points. (D) Several pathways and processes were enriched for differentially expressed genes following viral infection (m vs. Vm). (E) Top activated (red) or repressed (blue) upstream regulators following virus infection.
