Figure 4

Relative abundance (%) of bacterial phyla and Firmicutes/Bacteroidetes ratio in the caecal content of mice subjected to hypergravity at 2G and 3G compared to control mice (1G). A significant decrease of Verrucomicrobia (p = 0.0095) was noted in 3G samples by comparison to 2G samples. Significant lower levels of Proteobacteria (p = 0.0224 and 0.0095) were noted in 3G samples by comparison to 1G and to 2G samples (p = 0.0224 and p = 0.0095, respectively). Furthermore, higher levels of Deferribacteres (p = 0.078) were noted in 3G samples by comparison to 1G samples. Statistical analyses were done using the Mann-Whitney U test.