Figure 2
From: Depletion of Intestinal Microbiome Partially Rescues Bone Loss in Sickle Cell Disease Male Mice
Microbiome depletion with Abx improved decreased body weight, hindlimb BMD, and BMC in SCD male mice. (a) Body weight. (b) Hindlimb BMD and (c) BMC were significantly decreased in SCD-H2O mice compared with Ctrl-H2O mice and Abx treatment significantly increased hindlimb BMD and BMC in SCD mice. n = 4 mice/group. Data are mean ± SE. *p < 0.05 compared with Ctrl-H2O; #p < 0.05 compared with corresponding H2O group by two-way ANOVA.
