Figure 2 | Scientific Reports

Figure 2

From: Methylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancers

Figure 2

Methylation levels across IDHmut cancers. Volcano plots comparing CpG methylation levels of IDHmut versus IDHwt in (a) glioma, (b) AML, (c) cholangiocarcinoma, and (d) melanoma. Difference of mean methylation (x-axis) and significance of the difference (y-axis). Each point represents a unique CpG site. Hypermethylation is represented by a delta beta ≥0.15 and FDR-corrected P  < 0.05 shown in red, and hypomethylation by delta beta ≤−0.15 and FDR-corrected P  < 0.05.

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