Figure 5 | Scientific Reports

Figure 5

From: Methylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancers

Figure 5

Gene Set Enrichment Analysis (GSEA) showing gene sets in an interaction network for (a) glioma, (b) AML, (c) cholangiocarcinoma, and (d) melanoma. Each circular node represents enriched gene sets, where node color intensity corresponds with statistical significance (P-value). Blue nodes represent negative enrichment and red nodes represent positive enrichment. Edges (grey connection lines) represent overlap between gene sets with line thickness correlating to the degree of overlap. Networks of nodes that reflect generic function were circled and assigned group labels.

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