Figure 1 | Scientific Reports

Figure 1

From: Antibiotic treatment and flares of rheumatoid arthritis: a self-controlled case series study analysis using CPRD GOLD

Figure 1

Example schematic of SCCS study type for a patient with two antibiotic treatment periods. Treatment periods (highlighted in green) are the exposures, and varying risk windows are observation periods in to which the outcome of interest (RA flare) may or may not occur. Baseline risk periods account for increasing patient age, and only RA-diagnosed patients were enrolled into the study.

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