Figure 2 | Scientific Reports

Figure 2

From: Social defeat stress causes selective attenuation of neuronal activity in the ventromedial prefrontal cortex

Figure 2

Physiological characteristics of vmPFC 20–40 Hz events in control mice. (A) LFP power spectrogram constructed from LFP traces magnified from the shaded regions in Fig. 1E. (B) Simultaneous LFP recordings from the dmPFC and vmPFC during the occurrence of a vmPFC 20–40 Hz event. Each panel shows typical unfiltered traces (top), 20–40 Hz-filtered LFP traces (middle), and the corresponding z-scored RMS amplitudes (bottom). (C) The average frequency of 20–40 Hz events during SI tests plotted against variable detection thresholds of z-scored amplitudes (n = 18 electrodes from 11 mice (vmPFC), 15 electrodes from 11 mice (dmPFC), and 11 electrodes from 8 mice (ACC)). *P < 0.05, Mann–Whitney U test followed by Bonferroni correction, vmPFC versus dmPFC and vmPFC versus ACC. (D) Distribution of vmPFC 20–40 Hz event intervals between two neighboring 20–40 Hz events (n = 352 intervals). (E,F) Distribution of duration (E) and oscillation frequency (F) of individual 20–40 Hz events (n = 382 events).

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