Table 1 Correlation between the expression of ANO1 mRNA in PBMCs and its expression in tissues from 81 patients with GISTs.

From: Detection of ANO1 mRNA in PBMCs is a promising method for GISTs diagnosis

[0 = negative]

IHC scores for ANO1 in tissues [0 = negative]

[1–3]

[4–6]

p value

No. of GISTs patients (Total = 81)

9

42

30

Expression of ANO1 mRNA (Median and range)

1.0e−5 (3.0e−6–5.0e−4)

3.0e−4 (4.0e−5–6.0e−3)

6.0e−3 (7.0e−5–4.0e−2) < 0.05*

  1. Among the 81 cases of GISTs, 9 cases were negative for ANO1 expression, and the mean value of ANO1 mRNA expression in their PBMCs was 1.0e−5. There were 42 cases with low expression of ANO1, and the mean expression of ANO1 mRNA in their PBMCs was 3.0e−4. There were 30 cases with high expression of ANO1, and the mean value of ANO1 mRNA expression in their PBMCs was 6.0e−3. The results of analysis of variance showed that the mean values of ANO1 mRNA in the three groups were statistically significant.
  2. *p < 0.05 indicates statistical significance.
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