Figure 4

Spatiotemporal profiles of changes for GC and MC firing rates. (a) Color-coded panel, firing rate change by position for individual cells, using pre trials as references. Cells are sorted by the position of maximum change (in absolute value). Lines, average firing rate changes (absolute values) by position for blocks of 8 trials, with MC averages superimposed to GC averages (right panels) to facilitate comparison (MC, n = 40 cells, GC, n = 40 cells). Note that most changes are near the added cue. (b) Change in normalized firing rate over trials, using pre trials as reference. Color-coded panel, individual cells sorted according to firing rate changes. Middle, population average (lines) and s.e.m (error bars) for firing rate change (significance relative to 0). Note that population firing rates are on average preserved. Bottom, absolute values of changes (significance relative to trials 21–25). Note the progressive development for GCs. (c) Change in firing rate (normalized) over time, using the 50-s time period preceding cue addition as reference. Color-coded panel, individual cells sorted according to firing rate changes. Bottom, population mean firing rates (significance relative to pre trials). *p < 0.05, **p < 0.01, ***p < 0.001, unpaired t-test.