Figure 4
Expression of iron-related genes in WT, Heph KO, and Cp KO astrocytes with or without iron treatment. Cp (A), Fpn1(+IRE) (B), L-ferritin (C), H-ferritin (D), Tfrc (E) and Dmt1(+IRE) (F) mRNA levels were evaluated by quantitative PCR in WT, Heph KO, and Cp KO astrocytes treated with medium alone or with 40 μM iron. Data are representative of at least three independent experiments. UD: undetectable; values are presented as the means ± SEM; *P < 0.05, different from WT control; #P < 0.05, different from Heph KO control; &P < 0.05, different from Cp KO control, as determined by unpaired Student’s t-test.
