Table 1 Diagnostic performance of various indexes in differentiating patients with Sjögren’s syndrome (SS) from patients suspected of having SS.
From: Whole-Volume ADC Histogram Analysis in Parotid Glands to Identify Patients with Sjögren’s Syndrome
Parameters | Cutoff value | Sensitivity | Specificity | Accuracy | AUC | P |
|---|---|---|---|---|---|---|
Anti-SSA and/or anti-SSB antibody | + | 75.0% | 62.5% | 71.1% | 0.688 | 0.009* |
Ocular tests | + | 40.4% | 66.7% | 48.7% | 0.359 | 0.566 |
X-ray sialography | + | 73.1% | 58.3% | 68.4% | 0.657 | <0.029* |
Lip biopsy | + | 34.6% | 91.7% | 52.6% | 0.631 | 0.067 |
MR morphology grade | Grades 1–3 | 59.6% | 100.0% | 72.4% | 0.798 | <0.001* |
ADC (×10−6 mm2/s) | <647.4 | 25.0% | 87.5% | 44.7% | 0.522 | 0.759 |
ADCmean (×10−6 mm2/s) | <669.6 | 28.8% | 87.5% | 47.4% | 0.534 | 0.639 |
Skewness | <0.571 | 40.4% | 87.5% | 47.4% | 0.589 | 0.215 |
Kurtosis | >4.930 | 40.0% | 81.5% | 53.7% | 0.625 | 0.085 |
Entropy | >6.15 | 88.5% | 83.3% | 86.8% | 0.924 | <0.001* |
