Table 2 Summary of dose falloff results in CyberKnife IRIS- and MLC-based plans.

From: Plan Quality and Secondary Cancer Risk Assessment in Patients with Benign Intracranial Lesions after Radiosurgery using the CyberKnife M6 Robotic Radiosurgery System

 

Number of Plans

R50%

R10%

Ratio(MLC/IRIS)

P-value (Wilcoxon’s signed-rank)

IRIS

MLC

IRIS

MLC

R50%

R10%

R50%

R10%

All cases

15

5.52 ± 1.41 (5.74)

4.64 ± 1.20 (4.56)

54.00 ± 25.60 (45.74)

54.99 ± 28.92 (45.56)

0.84

1.02

0.006

0.865

Target volume ≤1 cc

3

5.65 ± 1.17 (6.40)

5.95 ± 1.17 (5.86)

71.94 ± 18.97 (80.07)

95.02 ± 8.89 (98.13)

1.05

1.32

0.593

0.109

1 cc < Target volume ≤10 cc

7

5.40 ± 1.83 (4.95)

4.26 ± 1.18 (4.01)

57.85 ± 29.30 (48.38)

54.37 ± 24.94 (45.56)

0.79

0.94

0.028

0.612

Target volume >10 cc

5

5.61 ± 0.63 (5.74)

4.39 ± 0.49 (4.20)

37.84 ± 8.54 (37.15)

31.84 ± 9.62 (32.06)

0.78

0.84

0.043

0.043

  1. Notes: Data represent the mean ± SD (median); Significance was defined as P < 0.05 on Wilcoxon’s Signed-Rank Test; R50%, represents the ratio of the volume covered by the 50% prescription isodose line of the maximum target dose (D50%) to the target volume; R10%, represents the ratio of the volume covered by the 10% prescription isodose line of the maximum target dose (D10%) to the target volume.
  2. Abbreviations: MLC, Multileaf collimator; IRIS, Iris collimator; EAR, Excess Absolute Risk; CI, conformal index.
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