Table 3 Genes up and down-regulated in luxS during co-culture with B. fragilis relative to the WT C. difficile monoculture.

From: Clostridioides difficile LuxS mediates inter-bacterial interactions within biofilms

No

Gene ID

log2FoldChange

Gene Annotation

1

CDR20291_0491

1.0964355

RNA methylase

2

CDR20291_0492

1.1802034

hypothetical protein

3

CDR20291_0493

1.0076105

outer membrane lipoprotein

4

CDR20291_0715

1.6245725

N-acetylmuramoyl-L-alanine amidase

5

CDR20291_1366

0.9274027

ferrous ion transport protein

6

CDR20291_1374

1.1651176

iron-sulfur protein

7

CDR20291_1691

1.4187304

nitrite and sulfite reductase subunit

8

CDR20291_1716

1.3143654

thiol peroxidase

9

CDR20291_1717

1.110872

hypothetical protein

10

CDR20291_1934

1.5456229

hypothetical protein

11

CDR20291_1936

1.3368874

GntR family transcriptional regulator

12

CDR20291_1937

1.3736945

ABC transporter ATP-binding protein

13

CDR20291_2389

1.2619709

competence protein

14

CDR20291_2830

1.11333

ribonucleoside-diphosphate reductase subunit alpha

15

CDR20291_2928

1.7538156

PTS system transporter subunit IIABC

16

CDR20291_2930

1.5713168

trehalose-6-phosphate hydrolase

17

CDR20291_3075

1.3649687

osmoprotectant ABC transporter substrate-binding/permease

18

CDR20291_3104

0.8099098

sigma-54-dependent transcriptional activator

19

CDR20291_3434

1.4402419

homocysteine S-methyltransferase

20

CDR20291_0025

−1.32053

acetoin:2%2C6-dichlorophenolindophenol oxidoreductase subunit alpha

21

CDR20291_0615

−0.86915

nucleotide phosphodiesterase

22

CDR20291_0802

−2.260047

ABC transporter substrate-binding protein

23

CDR20291_0911

−1.24181

electron transfer flavoprotein subunit beta

24

CDR20291_1359

−0.850952

hypothetical protein

25

CDR20291_1370

−1.124726

tyrosyl-tRNA synthetase

26

CDR20291_1497

−1.456296

phosphomethylpyrimidine kinase

27

CDR20291_1498

−1.727285

hydroxyethylthiazole kinase

28

CDR20291_1499

−1.276387

thiamine-phosphate pyrophosphorylase

29

CDR20291_1591

−1.51799

dinitrogenase iron-molybdenum cofactor

30

CDR20291_1901

−1.832663

ABC transporter ATP-binding protein

31

CDR20291_1902

−1.875507

ABC transporter substrate-binding protein

32

CDR20291_1903

−1.659329

ABC transporter permease

33

CDR20291_1904

−1.638609

hypothetical protein

34

CDR20291_1925

−1.54806

flavodoxin

35

CDR20291_2474

−1.434272

DNA-directed RNA polymerase subunit omega

36

CDR20291_2515

−1.603951

amino acid permease family protein

37

CDR20291_2516

−1.176482

cobalt dependent x-pro dipeptidase

38

CDR20291_2660

−0.958814

teichuronic acid biosynthesis glycosyl transferase

39

CDR20291_2870

−2.335518

hypothetical protein

40

CDR20291_3142

−1.665916

pyrroline-5-carboxylate reductase

41

CDR20291_3143

−1.830481

formate acetyltransferase

42

CDR20291_3144

−1.643573

pyruvate formate-lyase 3 activating enzyme

  1. Note: P-adjusted value ≤ 0.05.