Table 1 Baseline patient characteristics according to fluorescein angiography (FA) and indocyanine green angiography (ICGA)-based classification in neovascular age-related macular degeneration.

From: Angiographic Subtypes of Neovascular Age-related Macular Degeneration in Korean: A New Diagnostic Challenge

Characteristics n = 339

Classic CNV n = 41

Occult CNV n = 30

MCV n = 91

PCV n = 123

RAP n = 54

P- value

Age, yrs

76.8 ± 5.6 (62~87)

72.9 ± 6.9 (59~87)

69.7 ± 8.0 (50~84)

70.4 ± 7.8 (50~90)

77.9 ± 5.9 (65~92)

<0.001a

Sex (M/F)

22/19

14/16

67/24

83/40

14/40

<0.001b

Bilaterality

22 (55.0%)

15 (50.0%)

21 (23.1%)

30 (24.4%)

26 (48.1%)

<0.001b

BCVA, Snellen (logMAR)

20/400 (1.34)

20/100 (0.69)

20/80 (0.60)

20/100 (0.70)

20/142 (0.84)

<0.001a

CST, μm

287.8 ± 123.2 (110~547)

328.9 ± 108.0 (140~580)

298.4 ± 87.7 (108~557)

309.5 ± 87.5 (144~645)

348.9 ± 133.8 (190~884)

0.036a

Subretinal hemorrhage

5 (13.2%)

2 (6.7%)

12 (13.2%)

28 (22.8%)

9 (17.3%)

0.161b

Type of FA

     

<0.001c

Classic CNV

41 (100%)

0

15 (16.5%)

42 (34.1%)

7 (13.0%)

 

Occult CNV

0

30 (100%)

76 (83.5%)

81 (65.9%)

30 (55.6%)

 

RAP

0

0

0

0

17 (31.5%)

 

ICGA findings

Hot spot

2 (4.9%)

1 (3.3%)

69 (75.8%)

117 (95.1%)

41 (75.9%)

<0.001b

Branching vascular network

6 (14.6%)

2 (6.7%)

91 (100.0%)

104 (84.6%)

3 (5.6%)

<0.001b

Plaque

3 (7.3%)

12 (40.0%)

5 (5.5%)

4 (3.3%)

11 (20.4%)

<0.001b

  1. CNV, choroidal neovascularization; MCV, microaneurysmal choroidal vasculopathy; PCV, polypoidal choroidal vasculopathy; RAP, retinal angiomatous proliferation; BCVA, best-corrected visual acuity; CST, central subfield thickness; FA, fluorescein angiography.
  2. Continuous variables are reported as mean ± standard deviation (range) values. All other data are n (%).
  3. aCalculated by one-way ANOVA.
  4. bCalculated by chi-square test.
  5. cCalculated by Kruskal-Wallis H test.
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